The tile on the top right is a ghost nano, and the card it has an affinity for is blink. If I am playing that blink against a ghost player, it's charge drops to a two. On the bottom right is the echidna, whose affinity card is growth. If I am using the echidna and play that card, the charge becomes two instead.
To start, each player picks which nano he wants to use, then draws a starting hand consisting of three 1's, two 2's,and one 3. The starting player then placed his tile in the center of the play area, plays a reaction card, and then draws a card. Then the next person builds off the first tile, and so on until someone's cache runs out of bots.